关于此课程

该课程将带你走进人类基因组生物学,着重从科学、社会与个体的角度介绍人类遗传特征。

学费
免费
学习时间
大约 3 MONTHS
难度
初级
你将获得

Rich Learning Content

Interactive Quizzes

Taught by Industry Pros

Self-Paced Learning

Student Support Community

开始你的旅程

学习这门免费课程,迈出通往编程入门(中/英)职业道路的第一步。

免费课程

基因组的故事

合作企业 23andMe

通过创新性的自主学习方式,掌握新技能,提升竞争力。

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课程讲师

Joanna Mountain
Joanna Mountain

讲师

Uta Francke
Uta Francke

讲师

23andMe Team
23andMe Team

讲师

Matthew Cook
Matthew Cook

讲师

Lauren Castellano
Lauren Castellano

讲师

你将学到什么

lesson 1

Introduction to traits and heredity

  • Trait variation and categorization.
  • Basic models of inheritance.
  • The connection via DNA.
lesson 2

Defining the genome

  • DNA structure and chromosomes.
  • The genome organization.
lesson 3

How a genome works

  • Protein coding genes, transcription, translation.
  • Discerning the genetic code and alleles.
lesson 4

Gene regulation

  • Non-coding DNA and regulatory regions of genes.
  • Transcription factors.
lesson 5

Transmission of genes and traits

  • Family relationships and pedigrees.
  • Inheritance patterns, allele dominance.
  • Chromosome dynamics.
lesson 6

Origin of mutation/variation

  • Types of mutations and various causes of mutation.
  • Allelic frequency, and the spread of alleles in a population.
lesson 7

How to obtain and interpret personal genetic information

  • Personalized genetics: sample acquisition, DNA extraction and processing.
  • Interpretation of results.
lesson 8

Simple genetic traits

  • Molecular causes of monogenic traits.
  • Loss-of-function vs. gain-of-function alleles, and dominance.
lesson 9

Multifactorial traits

  • Polygenic traits, qualitative and quantitative measures.
  • Twin studies, relative risk, and genome-wide association studies (GWAS).
lesson 10

Pharmacogenetics: genes and drugs

  • Pharmacokinetics and pharmacodynamics.
  • Alleles affecting drug metabolism.
  • Personalized medicine.

先修知识及要求

你不需要拥有遗传学知识,但了解细胞等基本生物学概念会很有帮助。

查看使用优达学城的技术要求

为什么学习这门课程?

你将学习到遗传、基因表达、突变和变异的基本原理,简单和复杂生物性状的发展过程,人类的起源和演化,及获得个体遗传信息。课程结束时,你将能够阅读和理解来自 23andme 等个人基因检测服务网站的遗传信息。

我将获得什么?
Instructor videos Learn by doing exercises Taught by industry professionals